Thioredoxin domain-containing protein 5

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August undefined, 2024

WebAug 28, 2024 · Endoplasmic reticulum protein thioredoxin domain containing 5 (TXNDC5) is a novel mediator of endothelial dysfunction and atherosclerosis, European Heart Journal, Volume 39, ... (HAECs) stimulated with atherogenic disturbed flow, we identified thioredoxin domain containing 5 (TXNDC5), an endoplasmic reticulum (ER) protein with the enzyme ... WebFeb 1, 2024 · 3.3. Diverse thioredoxin activities regulate plant immunity. In the last decade it has become increasingly clear that different TRX enzymes play diverse roles in regulation of plant immune signalling. One of the first demonstrated roles of TRX in plant immunity came from studies of the tomato LRR-containing Cf-9 resistance protein that ...

Thioredoxin - an overview ScienceDirect Topics

WebThioredoxin domain containing 5 (TXNDC5), an ER-localized protein disulfide isomerase, was shown to facilitate ECM protein folding and to contribute to the stability of ECM … Web(thioredoxin domain containing 5), a cardiac fibroblast (CF)–enriched endoplasmic reticulum protein, as a potential novel mediator of cardiac fibrosis, and we completed experiments to test this hypothesis directly. Objective: The objective of this study was to determine the functional role of TXNDC5 in the pathogenesis of cardiac fibrosis. eucerin shop near me

A critical role of the thioredoxin domain containing protein 5 …

WebNov 14, 2024 · Amplified cDNA was sub-cloned in pET32a containing thioredoxin (Trx) and histidine (His) tags (Novagen). The resultant clone, the Trx-Gγ3 domain vector, was transformed in T7 Express lysY / I q E. coli (New England Biolabs), and the recombinant protein was synthesized and designated as the Trx-Gγ3 domain protein. The cDNA … WebTwo novel proteins, mimecan and thioredoxin domain–containing protein 5 (TXNDC5), were further validated by Western blot in 8 colorectal adenomas and 19 cancers that were matched with normal mucosa. All adenoma and cancer tissues did not express mimecan, but all normal mucosa did (P < 0.01). WebDec 1, 2024 · As a critical member of the PDI family, thioredoxin domain containing protein 5 (TXNDC5) assists the folding of newly synthesized peptides to their mature form … eucerin shoppers

Differential Expression of Mimecan and Thioredoxin …

P593Endoplasmic reticulum protein thioredoxin domain containing 5 …

WebMar 29, 2024 · Overactivated osteoclasts lead to many bone diseases, including osteoporosis and rheumatoid arthritis. The p38 MAPK (p38) is an essential regulator of the receptor activator of nuclear factor-κB ligand (RANKL)-mediated osteoclastogenesis and bone loss. We previously reported TAT conjugated thioredoxin-interacting protein … WebSep 28, 2024 · As a critical member of the PDI family, thioredoxin domain containing protein 5 (TXNDC5) assists the folding of newly synthesized peptides to their mature form through series of disulfide bond exchange reactions. Interestingly, TXNDC5 is frequently found overexpressed in specimens of many human diseases including various types of cancer. fireworks yellowWebApr 14, 2024 · The protein (0.5 µM final concentration) and pure buffer (blank) were placed into a 96-well plate and mixed with the GTP-containing master mix, resulting in a final volume of 150 µl per well. firework synonyms list

"WebMar 8, 2013 · Thioredoxin-interacting protein (TxNIP) is up-regulated by high glucose and is associated with oxidative stress. ... (ifu)/ml. Briefly, a mixture containing DMEM with 15% FBS, 2.5 mg/ml of poly-l-lysine and adenovirus was added to subconfluent Hcb-19 MC and incubated for 24 h before growth arrest. ... by its α-arrestin domain . " - Thioredoxin domain-containing protein 5

Thioredoxin domain-containing protein 5

The role and mechanism of TXNDC5 in diseases

WebProteomics and gene expression analyses of squalene-supplemented mice identify microsomal thioredoxin domain-containing protein 5 changes associated with hepatic steatosis Author links open overlay panel Adela Ramírez-Torres a , Sílvia Barceló-Batllori b , Roberto Martínez-Beamonte a e , María A. Navarro c e , Joaquín C. Surra a e ... WebApr 7, 2024 · The C-terminal region of RNF111 shares approximately 45% sequence homology with its related E3 RNF165, and this sequence homology is particularly strong (> 80%) within the core RING domain [27, 28] (Fig. 1d).We therefore performed Flag co-immunoprecipitation (co-IP) of HA-UBXN7 with Flag-RNF165-WT or the size equivalent C …

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WebTXNDC17 encodes a 14-kD protein that has a thioredoxin (TRX, or TXN; 187700) fold and a TRX-like active-site sequence. TXNDC17 and TRX function in reducing protein disulfide bonds and in denitrosylation of nitrosylated proteins and thiols. In addition, TXNDC17 has a unique role in reduction of L-cystine for synthesis of glutathione ( Pader et ... WebAug 8, 2024 · Thioredoxin domain-containing protein 5 (TXNDC5) is a member of the protein disulfide isomerase (PDI) family. It can promote the formation and rearrangement …

WebDec 4, 2024 · thioredoxin domain-containing protein 17, 14 kDa thioredoxin-related protein, protein 42-9-9, testicular tissue protein Li 214, thioredoxin (Trx)-related protein, 14 kDa, thioredoxin-like 5, thioredoxin-like protein 5. GeneRIFs: Gene References Into Functions. Cellular S-denitrosylases: Potential role and interplay of Thioredoxin, TRP14, and ... WebAbstract. Thioredoxin (Trx) is an inflammation-inducible small oxidoreductase protein ubiquitously expressed in all organisms. Trx acts both intracellularly and extracellularly …

WebTXNDC5, thioredoxin domain containing 5 Vertebrate Orthologs 3 Vertebrate Orthology Source. Alliance of Genome Resources. Human Ortholog ... PR:000016863 thioredoxin domain-containing protein 5 (term hierarchy) EC. 1.8.4.-, 5.3.4.1. InterPro Domains. IPR005788 Disulphide isomerase. WebProteomics and gene expression analyses of squalene-supplemented mice identify microsomal thioredoxin domain-containing protein 5 changes associated with hepatic …

WebTxndc5. Name. thioredoxin domain containing 5. Synonyms. ERp46, PC-TRP. Feature Type. protein coding gene. IDs. MGI:2145316.

WebPossesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast (By similarity). This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The … eucerin shop onlineWebTwo novel proteins, mimecan and thioredoxin domain–containing protein 5 (TXNDC5), were further validated by Western blot in 8 colorectal adenomas and 19 cancers that were … fireworks year 1WebSep 19, 2024 · disintegrin and metalloproteinase domain-containing protein 10: 3.24: 1.7: 21.76: 2.75 × 10 −3: 0.028: yes ... MLRs were set up as described in figure 5 and in the presence of the thioredoxin inhibitor PX-12, and analysed by flow cytometry at the time points indicated. fireworks xparticlesWebJul 8, 2024 · Interestingly, although several thioredoxin domain-containing proteins were present in the oxidoreductase enzyme cluster, two primary members of this class, thioredoxin reductase 1 and 2 were ... eucerin shower oil bootsWebJan 18, 2024 · T hiosulfate Sulfurtransferase like Domain Containing 1 Protein Interacts with Thioredoxin Marouane Libiad 1 ǂ , Nicole Motl 1 ǂ , David L. Akey 2 , Naoya Sakamoto 4 , Eric R. Fearon 3 , Janet L ... firework symbolWebFeb 23, 2024 · Kinetic studies with a combination of sulfur donors and acceptors reveal that TSTD1 exhibits a low Km for thioredoxin as a sulfane sulfur acceptor and that it utilizes thiosulfate inefficiently as a sulfur donor. The active site exposure and its interaction with thioredoxin suggest that TSTD1 might play a role in sulfide-based signaling. fireworks yeovilWebMar 29, 2024 · thioredoxin domain containing 15 provided by HGNC Primary source HGNC:HGNC:20652 MIM:617778; AllianceGenome:HGNC:20652 Gene type protein coding … eucerin shower