Biphenotypic sarcoma
WebBiphenotypic sinonasal sarcoma (BSNS) is an emerging subtype of sinonasal malignancy. It has not been previously well-studied but has characteristic gene fusion products and associated phenotypic features unique to it. Although rare, it has the potential to become large and infiltrate into bone over a prolonged period, with nonspecific ... WebJan 16, 2024 · Biphenotypic sinonasal sarcoma (BSNS) is a rare locally aggressive site-specific sarcoma that arises in the sinonasal tract and is characterized by PAX3 rearrangements. First recognized as “low grade sinonasal sarcoma with neural and myogenic differentiation” by Lewis et al., this tumor had undoubtedly been previously …
Biphenotypic sarcoma
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WebBiphenotypic sinonasal sarcoma: 2-3:1 female, 40-60 y: Infiltrative spindled cells in intersecting fascicules, “herringbone” pattern: Superior sinonasal tract and ethmoids: Nerve sheath tumors, synovial sarcomas, rhabdomyosarcomas: Renal cell-like adenocarcinoma: 2:1 female, 50-70 y: WebSarcomas with MEIS1-NCOA2 fusions have been so far reported in 2 cases each of primitive renal sarcomas and intraosseous pelvic rhabdomyosarcomas. Their histologic spectrum, anatomic distribution, and clinical behavior remain poorly defined. In this study, we report 6 additional spindle cell sarcomas with MEIS1-NCOA2 or NCOA1 fusions that …
WebJan 16, 2024 · Biphenotypic sinonasal sarcoma (BSNS) is a rare locally aggressive site-specific sarcoma that arises in the sinonasal tract and is characterized by PAX3 … WebOct 1, 2024 · Biphenotypic sinonasal sarcoma is a rare neoplastic entity, thus far reported to arise only in the nasal cavity, sinuses, and adjacent tissues. It is important to …
WebApr 5, 2024 · Biphenotypic sinonasal sarcoma is a rare entity only recently described in 2012. 1 It was included in the most recent edition of the World Health Organization … WebJan 16, 2024 · Introduction. Biphenotypic sinonasal sarcoma (BSNS) is a rare locally aggressive site-specific sarcoma that arises in the sinonasal tract and is characterized by PAX3 rearrangements. First recognized as “low grade sinonasal sarcoma with neural and myogenic differentiation” by Lewis et al., this tumor had undoubtedly been previously …
WebBiphenotypic sinonasal sarcoma (BSNS) is a rare, slow-growing soft tissue sarcoma of the sinonasal tract, typically presenting with nonspecific obstructive nasal symptoms. Although recurrences are common, no metastases have been reported, and only 1 …
WebNational Center for Biotechnology Information can be realizedWebJan 29, 2024 · Biphenotypic sinonasal sarcoma affects adults with a male-to-female ratio of 1:2 with a mean age of 49–51 years.[7-9] Our case was a male with a mean age of 48 … can be recognizedWebBackground Biphenotypic sinonasal sarcoma is a recently described malignancy showing dual differentiation with both myogenic and neural elements. Due to its histologic … can bereavement cause anxietyWebObjectives: Biphenotypic sinonasal sarcoma (BSNS), previously low-grade sinonasal sarcoma with neural and myogenic features, is a rare tumor of the sinonasal tract first described in 2012. Due to its rarity, limited literature is available in providing clinicians with a standardized treatment regimen, particularly in cases of positive surgical ... can be read backwards and forwardsWebBiphenotypic sinonasal sarcoma: Report of 3 cases with a review of literature. Shenon Sethi, Brittany Cody, Nada A. Farhat, Mark D. Pool, Nora Katabi. Article 200491 ... select article Atypical clear cell sarcoma of the pleura presenting as large pleural effusion with 22q12 abnormality: A challenging case with twists and turns. can bereavement cause ptsdWebBiphenotypic sinonasal sarcoma (SNS) is a newly described tumor of the nasal and paranasal areas. Here we report a recurrent chromosomal translocation in SNS, t(2;4)(q35;q31.1), resulting in a PAX3-MAML3 fusion protein that is a potent transcriptional activator of PAX3 response elements. The SNS phenotype is characterized by aberrant … can bereavement make you illWebOct 18, 2024 · (1) Background: Biphenotypic sinonasal sarcoma (BSNS) is a rare low-grade neoplasm of the sinonasal tract. It is characterized by specific PAX3 gene rearrangements and both myogenic and neural differentiation. The purpose of the study was to describe the histologic, immunohistochemical and molecular features of BSNS and … can bereavement be used for a miscarriage